Expression of TMEM116 in cancer - Summary

CANCER ATLAS

Gene description

Transmembrane protein 116

Protein class

Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA040720

GENE INFORMATION
Gene name	TMEM116 (HGNC Symbol)
Synonyms	FLJ90167
Description	Transmembrane protein 116 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q24.13
Chromosome location (bp)	111931282 - 112013185
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000198270 (version 83.38)
Entrez gene	89894
UniProt	Q8NCL8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NCL8
Antibodypedia	TMEM116 antibodies

PROTEIN BROWSER

TMEM116-001	TMEM116-003	TMEM116-005	TMEM116-007	TMEM116-009	TMEM116-010	TMEM116-012	TMEM116-013	TMEM116-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM116-001 ENSP00000447731 ENST00000552374	Q8NCL8 [Direct mapping] Transmembrane protein 116 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	337 aa 38 kDa	No	4
TMEM116-003 ENSP00000449163 ENST00000549537	G3V1Z3 [Direct mapping] Transmembrane protein 116; Transmembrane protein 116, isoform CRA_c Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	151 aa 17.3 kDa	No	1
TMEM116-005 ENSP00000450377 ENST00000550831	Q8NCL8 [Direct mapping] Transmembrane protein 116 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	245 aa 27.5 kDa	No	2
TMEM116-007 ENSP00000347620 ENST00000355445	Q8NCL8 [Direct mapping] Transmembrane protein 116 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	302 aa 33.8 kDa	Yes	3
TMEM116-009 ENSP00000450060 ENST00000550233	F8VQZ8 [Direct mapping] Transmembrane protein 116 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all		51 aa 5.8 kDa	Yes	1
TMEM116-010 ENSP00000449774 ENST00000549425	F8VWU6 [Direct mapping] Transmembrane protein 116 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	106 aa 12 kDa	No	1
TMEM116-012 ENSP00000446516 ENST00000550037	F8VNZ8 [Direct mapping] Transmembrane protein 116 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	175 aa 19.6 kDa	No	2
TMEM116-013 ENSP00000446766 ENST00000546962	F8W1L7 [Direct mapping] Transmembrane protein 116 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		74 aa 8.1 kDa	Yes	0
TMEM116-014 ENSP00000474027 ENST00000550800	S4R388 [Direct mapping] Transmembrane protein 116 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	104 aa 11.4 kDa	No	1