Expression of ZNF43 in cancer - Summary

CANCER ATLAS

Gene description

Zinc finger protein 43

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA050271

GENE INFORMATION
Gene name	ZNF43 (HGNC Symbol)
Synonyms	HTF6, KOX27, ZNF39L1
Description	Zinc finger protein 43 (HGNC Symbol)
Entrez gene summary	This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p12
Chromosome location (bp)	21804949 - 21852125
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000198521 (version 83.38)
Entrez gene	7594
UniProt	P17038 (UniProt - Evidence at transcript level)
neXtProt	NX_P17038
Antibodypedia	ZNF43 antibodies

PROTEIN BROWSER

ZNF43-001	ZNF43-002	ZNF43-003	ZNF43-007	ZNF43-008	ZNF43-010	ZNF43-011	ZNF43-012	ZNF43-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF43-001 ENSP00000347045 ENST00000354959	P17038 [Direct mapping] Zinc finger protein 43 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	809 aa 94.1 kDa	No	0
ZNF43-002 ENSP00000469645 ENST00000595461	P17038 [Direct mapping] Zinc finger protein 43 A0A024R7P7 [Target identity:100%; Query identity:100%] Zinc finger protein 43 (HTF6), isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	803 aa 93.5 kDa	No	0
ZNF43-003 ENSP00000469578 ENST00000594012	P17038 [Direct mapping] Zinc finger protein 43 A0A024R7P7 [Target identity:100%; Query identity:100%] Zinc finger protein 43 (HTF6), isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	803 aa 93.5 kDa	No	0
ZNF43-007 ENSP00000471176 ENST00000593551	M0QXI2 [Direct mapping] Zinc finger protein 43 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	60 aa 7.1 kDa	No	0
ZNF43-008 ENSP00000470275 ENST00000598381	P17038 [Direct mapping] Zinc finger protein 43 A0A024R7P7 [Target identity:100%; Query identity:100%] Zinc finger protein 43 (HTF6), isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	803 aa 93.5 kDa	No	0
ZNF43-010 ENSP00000471373 ENST00000598288	M0R3D5 [Direct mapping] Zinc finger protein 43 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	84 aa 9.8 kDa	No	0
ZNF43-011 ENSP00000470996 ENST00000596899	M0R0T7 [Direct mapping] Zinc finger protein 43 Show all	Predicted intracellular proteins Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] Show all	53 aa 6.6 kDa	No	0
ZNF43-012 ENSP00000469424 ENST00000599906	M0QYJ6 [Direct mapping] Zinc finger protein 43 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] Show all	121 aa 14.4 kDa	No	0
ZNF43-201 ENSP00000350085 ENST00000357491	A0A087WSW2 [Direct mapping] Zinc finger protein 43 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	818 aa 95.1 kDa	No	0