Expression of C6orf89 in cancer - Summary

CANCER ATLAS

Gene description

Chromosome 6 open reading frame 89

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA012548

GENE INFORMATION
Gene name	C6orf89 (HGNC Symbol)
Synonyms	BRAP, FLJ25357
Description	Chromosome 6 open reading frame 89 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p21.2
Chromosome location (bp)	36871870 - 36928964
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198663 (version 83.38)
Entrez gene	221477
UniProt	Q6UWU4 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UWU4
Antibodypedia	C6orf89 antibodies

PROTEIN BROWSER

C6orf89-001	C6orf89-002	C6orf89-003	C6orf89-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C6orf89-001 ENSP00000352316 ENST00000359359	Q5TDC5 [Direct mapping] Bombesin receptor-activated protein C6orf89; Chromosome 6 open reading frame 89, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		241 aa 27.9 kDa	No	0
C6orf89-002 ENSP00000347322 ENST00000355190	Q6UWU4 [Direct mapping] Bombesin receptor-activated protein C6orf89 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030496 [midbody] GO:0042060 [wound healing] GO:0045787 [positive regulation of cell cycle] GO:0050673 [epithelial cell proliferation] Show all	354 aa 40.7 kDa	No	1
C6orf89-003 ENSP00000362789 ENST00000373685	Q6UWU4 [Direct mapping] Bombesin receptor-activated protein C6orf89 A0A024RCY0 [Target identity:100%; Query identity:100%] Chromosome 6 open reading frame 89, isoform CRA_b Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030496 [midbody] GO:0042060 [wound healing] GO:0045787 [positive regulation of cell cycle] GO:0050673 [epithelial cell proliferation] Show all	347 aa 39.9 kDa	No	1
C6orf89-004 ENSP00000475947 ENST00000480824	Q6UWU4 [Direct mapping] Bombesin receptor-activated protein C6orf89 A0A024RCY0 [Target identity:100%; Query identity:100%] Chromosome 6 open reading frame 89, isoform CRA_b Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030496 [midbody] GO:0042060 [wound healing] GO:0045787 [positive regulation of cell cycle] GO:0050673 [epithelial cell proliferation] Show all	347 aa 39.9 kDa	No	1