Expression of SUCNR1 in cancer - Summary

CANCER ATLAS

Gene description

Succinate receptor 1

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Renal cancer

STAINING SUMMARY

CAB022745

GENE INFORMATION
Gene name	SUCNR1 (HGNC Symbol)
Synonyms	GPR91
Description	Succinate receptor 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009]
Chromosome	3
Cytoband	q25.1
Chromosome location (bp)	151873643 - 151884619
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198829 (version 83.38)
Entrez gene	56670
UniProt	Q9BXA5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BXA5
Antibodypedia	SUCNR1 antibodies

PROTEIN BROWSER

SUCNR1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SUCNR1-001 ENSP00000355156 ENST00000362032	Q9BXA5 [Direct mapping] Succinate receptor 1 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0070062 [extracellular exosome] Show all	334 aa 38.7 kDa	No	7