Expression of TOX in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Thymocyte selection-associated high mobility group box

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Glioma

STAINING SUMMARY

HPA018322

GENE INFORMATION
Gene name	TOX (HGNC Symbol)
Synonyms	KIAA0808, TOX1
Description	Thymocyte selection-associated high mobility group box (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.[provided by RefSeq, Apr 2009]
Chromosome	8
Cytoband	q12.1
Chromosome location (bp)	58805418 - 59119208
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198846 (version 83.38)
Entrez gene	9760
UniProt	O94900 (UniProt - Evidence at transcript level)
neXtProt	NX_O94900
Antibodypedia	TOX antibodies

PROTEIN BROWSER

TOX-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TOX-001 ENSP00000354842 ENST00000361421	O94900 [Direct mapping] Thymocyte selection-associated high mobility group box protein TOX Show all	Predicted intracellular proteins Transcription factors Other all-alpha-helical DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0005634 [nucleus] GO:0006338 [chromatin remodeling] GO:0006355 [regulation of transcription, DNA-templated] Show all	526 aa 57.5 kDa	No	0