Expression of ASB12 in cancer - Summary

CANCER ATLAS

Gene description

Ankyrin repeat and SOCS box containing 12

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA049542

GENE INFORMATION
Gene name	ASB12 (HGNC Symbol)
Synonyms	FLJ39577
Description	Ankyrin repeat and SOCS box containing 12 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Jan 2011]
Chromosome	X
Cytoband	q11.2
Chromosome location (bp)	64224196 - 64230631
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198881 (version 83.38)
Entrez gene	142689
UniProt	Q8WXK4 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WXK4
Antibodypedia	ASB12 antibodies

PROTEIN BROWSER

ASB12-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ASB12-001 ENSP00000355195 ENST00000362002	Q8WXK4 [Direct mapping] Ankyrin repeat and SOCS box protein 12 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0016567 [protein ubiquitination] GO:0035556 [intracellular signal transduction] Show all	318 aa 35 kDa	No	0