Expression of PNMA5 in cancer - Summary

CANCER ATLAS

Gene description

Paraneoplastic Ma antigen family member 5

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Testis cancer

STAINING SUMMARY

HPA044690

GENE INFORMATION
Gene name	PNMA5 (HGNC Symbol)
Synonyms	KIAA1934
Description	Paraneoplastic Ma antigen family member 5 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the paraneoplastic Ma antigen protein family. These proteins have been implicated in the development of paraneoplastic disorders resulting from an immune response directed against them. Paraneoplastic disorders are the result of an abnormal immune response to a tumor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2011]
Chromosome	X
Cytoband	q28
Chromosome location (bp)	152988824 - 152994127
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198883 (version 83.38)
Entrez gene	114824
UniProt	Q96PV4 (UniProt - Evidence at protein level)
neXtProt	NX_Q96PV4
Antibodypedia	PNMA5 antibodies

PROTEIN BROWSER

PNMA5-001	PNMA5-002	PNMA5-201	PNMA5-202	PNMA5-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PNMA5-001 ENSP00000354834 ENST00000361887	Q96PV4 [Direct mapping] Paraneoplastic antigen-like protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0042802 [identical protein binding] GO:0043065 [positive regulation of apoptotic process] Show all	448 aa 49.9 kDa	No	0
PNMA5-002 ENSP00000391130 ENST00000437210	C9J4L3 [Direct mapping] Paraneoplastic antigen-like protein 5 Show all	Predicted intracellular proteins Show all		140 aa 15.6 kDa	No	0
PNMA5-201 ENSP00000388850 ENST00000439251	Q96PV4 [Direct mapping] Paraneoplastic antigen-like protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0042802 [identical protein binding] GO:0043065 [positive regulation of apoptotic process] Show all	448 aa 49.9 kDa	No	0
PNMA5-202 ENSP00000392342 ENST00000452693	Q96PV4 [Direct mapping] Paraneoplastic antigen-like protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0042802 [identical protein binding] GO:0043065 [positive regulation of apoptotic process] Show all	448 aa 49.9 kDa	No	0
PNMA5-203 ENSP00000445775 ENST00000535214	Q96PV4 [Direct mapping] Paraneoplastic antigen-like protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0042802 [identical protein binding] GO:0043065 [positive regulation of apoptotic process] Show all	448 aa 49.9 kDa	No	0