We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Cancer tissues displayed weak to moderate cytoplasmic positivity. Strong staining was observed in a few cases of colorectal cancers and melanomas. Several lymphomas, skin and renal cancers were negative.
Majority of cancer tissues showed weak to moderate cytoplasmic positivity with additional membranous staining in a few cases. Carcinoids, skin, head and neck cancers were negative.
GENE INFORMATION
Gene name
DCAF12L1 (HGNC Symbol)
Synonyms
KIAA1892L, WDR40B
Description
DDB1 and CUL4 associated factor 12-like 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]