Cell atlas - LY6G5C - The Human Protein Atlas

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LY6G5C

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	LY6G5C
Gene description	Lymphocyte antigen 6 complex, locus G5C
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol.
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA038690
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

Nucleoplasm (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA038690	A-431	Nucleoplasm
	HPA038690	A-431	Cytosol
	HPA038690	U-2 OS	Nucleoplasm
	HPA038690	U-2 OS	Cytosol
	HPA038690	U-251 MG	Nucleoplasm
	HPA038690	U-251 MG	Cytosol

GENE INFORMATION
Gene name	LY6G5C (HGNC Symbol)
Synonyms	C6orf20, G5c, NG33
Description	Lymphocyte antigen 6 complex, locus G5C (HGNC Symbol)
Entrez gene summary	LY6G5C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]
Chromosome	6
Cytoband	p21.33
Chromosome location (bp)	31676684 - 31684040
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204428 (version 83.38)
Entrez gene	80741
UniProt	Q5SRR4 (UniProt - Evidence at protein level)
neXtProt	NX_Q5SRR4
Antibodypedia	LY6G5C antibodies

PROTEIN BROWSER

LY6G5C-001	LY6G5C-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LY6G5C-001 ENSP00000365023 ENST00000375863	H7BYB1 [Direct mapping] Lymphocyte antigen 6 complex locus protein G5c Show all	Predicted intracellular proteins Show all		225 aa 24.9 kDa	No	0
LY6G5C-003 ENSP00000372724 ENST00000383237	Q5SRR4 [Direct mapping] Lymphocyte antigen 6 complex locus protein G5c Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005576 [extracellular region] Show all	150 aa 16.7 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.