Cell atlas - APOM - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

APOM

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus

Human cell
	Golgi Apparatus

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	APOM
Gene description	Apolipoprotein M
Protein class	Plasma proteins Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the Golgi apparatus.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA051006
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the Golgi apparatus.

Main location

Golgi apparatus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA051006	Hep G2	Golgi apparatus

GENE INFORMATION
Gene name	APOM (HGNC Symbol)
Synonyms	ApoM, G3a, NG20
Description	Apolipoprotein M (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
Chromosome	6
Cytoband	p21.33
Chromosome location (bp)	31652416 - 31658210
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204444 (version 83.38)
Entrez gene	55937
UniProt	O95445 (UniProt - Evidence at protein level)
neXtProt	NX_O95445
Antibodypedia	APOM antibodies

PROTEIN BROWSER

APOM-001	APOM-002	APOM-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
APOM-001 ENSP00000365081 ENST00000375916	O95445 [Direct mapping] Apolipoprotein M Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001523 [retinoid metabolic process] GO:0005319 [lipid transporter activity] GO:0005543 [phospholipid binding] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0005887 [integral component of plasma membrane] GO:0007603 [phototransduction, visible light] GO:0009749 [response to glucose] GO:0016209 [antioxidant activity] GO:0033344 [cholesterol efflux] GO:0034361 [very-low-density lipoprotein particle] GO:0034362 [low-density lipoprotein particle] GO:0034364 [high-density lipoprotein particle] GO:0034365 [discoidal high-density lipoprotein particle] GO:0034366 [spherical high-density lipoprotein particle] GO:0034375 [high-density lipoprotein particle remodeling] GO:0034380 [high-density lipoprotein particle assembly] GO:0034384 [high-density lipoprotein particle clearance] GO:0034445 [negative regulation of plasma lipoprotein particle oxidation] GO:0042157 [lipoprotein metabolic process] GO:0042632 [cholesterol homeostasis] GO:0043691 [reverse cholesterol transport] GO:0070062 [extracellular exosome] Show all	188 aa 21.3 kDa	Yes	0
APOM-002 ENSP00000365085 ENST00000375920	O95445 [Direct mapping] Apolipoprotein M Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001523 [retinoid metabolic process] GO:0005319 [lipid transporter activity] GO:0005543 [phospholipid binding] GO:0005576 [extracellular region] GO:0005887 [integral component of plasma membrane] GO:0007603 [phototransduction, visible light] GO:0016209 [antioxidant activity] GO:0033344 [cholesterol efflux] GO:0034361 [very-low-density lipoprotein particle] GO:0034362 [low-density lipoprotein particle] GO:0034364 [high-density lipoprotein particle] GO:0034365 [discoidal high-density lipoprotein particle] GO:0034366 [spherical high-density lipoprotein particle] GO:0034375 [high-density lipoprotein particle remodeling] GO:0034380 [high-density lipoprotein particle assembly] GO:0034384 [high-density lipoprotein particle clearance] GO:0034445 [negative regulation of plasma lipoprotein particle oxidation] GO:0042632 [cholesterol homeostasis] GO:0043691 [reverse cholesterol transport] GO:0070062 [extracellular exosome] Show all	116 aa 13.1 kDa	No	0
APOM-003 ENSP00000365083 ENST00000375918	Q5SRP5 [Direct mapping] Apolipoprotein M Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		129 aa 14.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.