Expression of PRRC2A in cancer - Summary

CANCER ATLAS

Gene description

Proline-rich coiled-coil 2A

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA046791	CAB026383

GENE INFORMATION
Gene name	PRRC2A (HGNC Symbol)
Synonyms	BAT2, D6S51E, G2
Description	Proline-rich coiled-coil 2A (HGNC Symbol)
Entrez gene summary	A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]
Chromosome	6
Cytoband	p21.33
Chromosome location (bp)	31620720 - 31637771
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204469 (version 83.38)
Entrez gene	7916
UniProt	P48634 (UniProt - Evidence at protein level)
neXtProt	NX_P48634
Antibodypedia	PRRC2A antibodies

PROTEIN BROWSER

PRRC2A-001	PRRC2A-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRRC2A-001 ENSP00000365175 ENST00000376007	P48634 [Direct mapping] Protein PRRC2A Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0016020 [membrane] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] GO:0070062 [extracellular exosome] Show all	2157 aa 228.9 kDa	No	0
PRRC2A-002 ENSP00000365201 ENST00000376033	P48634 [Direct mapping] Protein PRRC2A Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0016020 [membrane] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] GO:0070062 [extracellular exosome] Show all	2157 aa 228.9 kDa	No	0