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PRAMEF19

CANCER ATLAS

Gene description

 PRAME family member 19

Protein class

 Predicted intracellular proteins

Protein evidence

 No evidence
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA057423

Tissue

Cancer staining
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

 Few cases of melanomas, colorectal, breast and ovarian cancers along with a rare case of seminoma exhibited weak to moderate nucleolar positivity. Remaining cancers were negative.

GENE INFORMATION

Gene name

 PRAMEF19

Synonyms

Description

 PRAME family member 19 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p36.21

Chromosome location (bp)

 13369067 - 13371693

Protein evidence

 No evidence (all genes)

Ensembl

 ENSG00000204480 (version 83.38)

Entrez gene

UniProt

 Q5SWL8 (UniProt - Inferred from homology)

neXtProt

 NX_Q5SWL8

Antibodypedia

 PRAMEF19 antibodies

PROTEIN BROWSER
PRAMEF19-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PRAMEF19-001
ENSP00000365269
ENST00000376101
Q5SWL8 [Direct mapping]
PRAME family member 19
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Predicted intracellular proteins
Show all
GO:0008284 [positive regulation of cell proliferation]
GO:0042974 [retinoic acid receptor binding]
GO:0043066 [negative regulation of apoptotic process]
GO:0045596 [negative regulation of cell differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0048387 [negative regulation of retinoic acid receptor signaling pathway]
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 410 aa
47.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.