Cell atlas - TRIM39 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

TRIM39

TISSUE

premium

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	TRIM39
Gene description	Tripartite motif containing 39
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	11
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA051120 , HPA059496
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA051120	A-431	Cytosol
	HPA051120	PC-3	No staining
	HPA051120	U-2 OS	Cytosol
	HPA059496	U-2 OS	Cytosol
	HPA059496	U-251 MG	Cytosol

GENE INFORMATION
Gene name	TRIM39 (HGNC Symbol)
Synonyms	RNF23
Description	Tripartite motif containing 39 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	p22.1
Chromosome location (bp)	30326479 - 30343729
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204599 (version 83.38)
Entrez gene	56658
UniProt	Q9HCM9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HCM9
Antibodypedia	TRIM39 antibodies

PROTEIN BROWSER

TRIM39-001	TRIM39-002	TRIM39-003	TRIM39-004	TRIM39-005	TRIM39-006	TRIM39-007	TRIM39-008	TRIM39-009	TRIM39-010	TRIM39-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRIM39-001 ENSP00000379797 ENST00000396548	Q9HCM9 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 A0A024RCR1 [Target identity:100%; Query identity:100%] Tripartite motif-containing 39, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0042802 [identical protein binding] GO:2000059 [negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process] GO:2001235 [positive regulation of apoptotic signaling pathway] Show all	488 aa 56.4 kDa	No	0
TRIM39-002 ENSP00000379796 ENST00000396547	Q9HCM9 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 A0A024RCP5 [Target identity:100%; Query identity:100%] Tripartite motif-containing 39, isoform CRA_b Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0042802 [identical protein binding] GO:2000059 [negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process] GO:2001235 [positive regulation of apoptotic signaling pathway] Show all	518 aa 59.7 kDa	No	0
TRIM39-003 ENSP00000365847 ENST00000376659	Q9HCM9 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 A0A024RCR1 [Target identity:100%; Query identity:100%] Tripartite motif-containing 39, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0042802 [identical protein binding] GO:2000059 [negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process] GO:2001235 [positive regulation of apoptotic signaling pathway] Show all	488 aa 56.4 kDa	No	0
TRIM39-004 ENSP00000379800 ENST00000396551	Q9HCM9 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 A0A024RCR1 [Target identity:100%; Query identity:100%] Tripartite motif-containing 39, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0042802 [identical protein binding] GO:2000059 [negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process] GO:2001235 [positive regulation of apoptotic signaling pathway] Show all	488 aa 56.4 kDa	No	0
TRIM39-005 ENSP00000405928 ENST00000458516	A2AAZ5 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] Show all	144 aa 16.2 kDa	No	0
TRIM39-006 ENSP00000406019 ENST00000428728	A2AAZ6 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] Show all	261 aa 30.1 kDa	No	0
TRIM39-007 ENSP00000405498 ENST00000428404	A2AAZ3 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] Show all	59 aa 6.4 kDa	No	0
TRIM39-008 ENSP00000397952 ENST00000428555	A2AAZ2 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		48 aa 5 kDa	No	0
TRIM39-009 ENSP00000388224 ENST00000420746	H0Y735 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0008270 [zinc ion binding] Show all	227 aa 26.3 kDa	No	0
TRIM39-010 ENSP00000394768 ENST00000440271	A2AAZ4 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] Show all	74 aa 8.2 kDa	No	0
TRIM39-201 ENSP00000365844 ENST00000376656	Q9HCM9 [Direct mapping] E3 ubiquitin-protein ligase TRIM39 A0A024RCP5 [Target identity:100%; Query identity:100%] Tripartite motif-containing 39, isoform CRA_b Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008270 [zinc ion binding] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0042802 [identical protein binding] GO:2000059 [negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process] GO:2001235 [positive regulation of apoptotic signaling pathway] Show all	518 aa 59.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.