Expression of TBC1D8 in cancer - Summary

CANCER ATLAS

Gene description

TBC1 domain family, member 8 (with GRAM domain)

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

CAB015211

GENE INFORMATION
Gene name	TBC1D8 (HGNC Symbol)
Synonyms	AD3, HBLP1, VRP
Description	TBC1 domain family, member 8 (with GRAM domain) (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q11.2
Chromosome location (bp)	101007617 - 101252866
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204634 (version 83.38)
Entrez gene	11138
UniProt	O95759 (UniProt - Evidence at transcript level)
neXtProt	NX_O95759
Antibodypedia	TBC1D8 antibodies

PROTEIN BROWSER

TBC1D8-001	TBC1D8-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TBC1D8-001 ENSP00000386856 ENST00000409318	J3KQ40 [Direct mapping] TBC1 domain family member 8 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		1155 aa 132.4 kDa	No	3
TBC1D8-011 ENSP00000366036 ENST00000376840	O95759 [Direct mapping] TBC1 domain family member 8 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0008015 [blood circulation] GO:0008284 [positive regulation of cell proliferation] GO:0016020 [membrane] GO:0043547 [positive regulation of GTPase activity] Show all	1140 aa 130.8 kDa	No	0