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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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PSG5
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

PSG5

Gene description

Pregnancy specific beta-1-glycoprotein 5

Protein class

Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

6
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (placenta)
GTEx:Not detected
FANTOM5:Tissue enriched (placenta)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in trophoblasts.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.

Reliability score

Approved based on 1 antibody.
HPA046327
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (placenta)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (placenta)

GENE INFORMATION

Gene name

PSG5 (HGNC Symbol)

Synonyms

FL-NCA-3, PSG

Description

Pregnancy specific beta-1-glycoprotein 5 (HGNC Symbol)

Entrez gene summary

The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

Chromosome

19

Cytoband

q13.31

Chromosome location (bp)

43166256 - 43186536

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204941 (version 83.38)

Entrez gene

5673

UniProt

Q15238 (UniProt - Evidence at protein level)

neXtProt

NX_Q15238

Antibodypedia

PSG5 antibodies

PROTEIN BROWSER

PSG5-001
PSG5-002
PSG5-003
PSG5-004
PSG5-005
PSG5-010

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSG5-001
ENSP00000382334
ENST00000366175
Q15238 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 5
A0A024R0S1 [Target identity:100%; Query identity:100%]
Pregnancy specific beta-1-glycoprotein 5, isoform CRA_a
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0007565 [female pregnancy]
Show all
335 aa
37.7 kDa
Yes 0
PSG5-002
ENSP00000386008
ENST00000407356
Q15238 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 5
A0A024R0S1 [Target identity:100%; Query identity:100%]
Pregnancy specific beta-1-glycoprotein 5, isoform CRA_a
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0007565 [female pregnancy]
Show all
335 aa
37.7 kDa
Yes 0
PSG5-003
ENSP00000344413
ENST00000342951
Q15238 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 5
A0A024R0S1 [Target identity:100%; Query identity:100%]
Pregnancy specific beta-1-glycoprotein 5, isoform CRA_a
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0007565 [female pregnancy]
Show all
335 aa
37.7 kDa
Yes 0
PSG5-004
ENSP00000385250
ENST00000404580
E7EQY3 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 5
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
333 aa
37.6 kDa
Yes 0
PSG5-005
ENSP00000386053
ENST00000407568
E9PC55 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 5
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
157 aa
17.5 kDa
Yes 0
PSG5-010
ENSP00000471866
ENST00000599812
M0R1G9 [Direct mapping]
Pregnancy-specific beta-1-glycoprotein 5
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
428 aa
48 kDa
Yes 0

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