Expression of NAP1L4 in cancer - Summary

CANCER ATLAS

Gene description

Nucleosome assembly protein 1-like 4

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

CAB011567

GENE INFORMATION
Gene name	NAP1L4 (HGNC Symbol)
Synonyms	NAP2
Description	Nucleosome assembly protein 1-like 4 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	p15.4
Chromosome location (bp)	2944431 - 2992377
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000205531 (version 83.38)
Entrez gene	4676
UniProt	Q99733 (UniProt - Evidence at protein level)
neXtProt	NX_Q99733
Antibodypedia	NAP1L4 antibodies

PROTEIN BROWSER

NAP1L4-001	NAP1L4-002	NAP1L4-003	NAP1L4-004	NAP1L4-011	NAP1L4-012	NAP1L4-013	NAP1L4-015	NAP1L4-016	NAP1L4-017	NAP1L4-018	NAP1L4-019	NAP1L4-020	NAP1L4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NAP1L4-001 ENSP00000369915 ENST00000380542	Q99733 [Direct mapping] Nucleosome assembly protein 1-like 4 A0A024RCC9 [Target identity:100%; Query identity:100%] Nucleosome assembly protein 1-like 4, isoform CRA_b Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006334 [nucleosome assembly] GO:0044822 [poly(A) RNA binding] GO:0051082 [unfolded protein binding] Show all	375 aa 42.8 kDa	No	0
NAP1L4-002 ENSP00000436397 ENST00000526115	Q99733 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006334 [nucleosome assembly] GO:0044822 [poly(A) RNA binding] GO:0051082 [unfolded protein binding] Show all	386 aa 44.1 kDa	No	0
NAP1L4-003 ENSP00000405912 ENST00000430811	C9J6D1 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	178 aa 20.3 kDa	No	0
NAP1L4-004 ENSP00000387783 ENST00000448187	C9JZI7 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	278 aa 31.8 kDa	No	0
NAP1L4-011 ENSP00000435327 ENST00000529361	E9PKT8 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	169 aa 19.2 kDa	No	0
NAP1L4-012 ENSP00000412048 ENST00000455338	C9J1B1 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	101 aa 11.4 kDa	No	0
NAP1L4-013 ENSP00000431799 ENST00000526842	E9PJJ2 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	128 aa 14.7 kDa	No	0
NAP1L4-015 ENSP00000432126 ENST00000530064	E9PS34 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	133 aa 15.3 kDa	No	0
NAP1L4-016 ENSP00000433512 ENST00000534372	E9PKI2 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	78 aa 8.6 kDa	No	0
NAP1L4-017 ENSP00000437130 ENST00000531291	E9PNW0 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	107 aa 12.2 kDa	No	0
NAP1L4-018 ENSP00000434759 ENST00000528968	E9PNJ7 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	140 aa 16 kDa	No	0
NAP1L4-019 ENSP00000382523 ENST00000399614	A8MXH2 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	156 aa 18.2 kDa	No	0
NAP1L4-020 ENSP00000436488 ENST00000532325	E9PP22 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	154 aa 17.3 kDa	No	0
NAP1L4-201 ENSP00000481412 ENST00000620138	Q99733 [Direct mapping] Nucleosome assembly protein 1-like 4 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006334 [nucleosome assembly] GO:0044822 [poly(A) RNA binding] GO:0051082 [unfolded protein binding] Show all	386 aa 44.1 kDa	No	0