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Moderate nuclear immunoreactivity was observed in few gliomas along with a singe case each of melanoma and cholangiocarcinoma. Strong nucleolar staining was observed in a single case of embryonal cancer. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
DPF3 (HGNC Symbol)
Synonyms
BAF45c, cer-d4, Cerd4, FLJ14079
Description
D4, zinc and double PHD fingers, family 3 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the D4 protein family. The encoded protein is a transcription regulator that binds acetylated histones and is a component of the BAF chromatin remodeling complex. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
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GO:0002230 [positive regulation of defense response to virus by host] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007399 [nervous system development] GO:0008150 [biological_process] GO:0008270 [zinc ion binding] GO:0016568 [chromatin modification] GO:0046872 [metal ion binding] GO:0071565 [nBAF complex] GO:0098779 [mitophagy in response to mitochondrial depolarization]
Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0002230 [positive regulation of defense response to virus by host] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007399 [nervous system development] GO:0008150 [biological_process] GO:0008270 [zinc ion binding] GO:0016568 [chromatin modification] GO:0046872 [metal ion binding] GO:0071565 [nBAF complex] GO:0098779 [mitophagy in response to mitochondrial depolarization]
Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002230 [positive regulation of defense response to virus by host] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007399 [nervous system development] GO:0008150 [biological_process] GO:0008270 [zinc ion binding] GO:0016568 [chromatin modification] GO:0046872 [metal ion binding] GO:0071565 [nBAF complex] GO:0098779 [mitophagy in response to mitochondrial depolarization]
