Tissue expression of CLEC6A - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CLEC6A
Gene description	C-type lectin domain family 6, member A
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (appendix, lung)
GTEx:	Not detected
FANTOM5:	Tissue enhanced (appendix, lung)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (appendix, lung)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Not detected
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (appendix, lung)

GENE INFORMATION
Gene name	CLEC6A (HGNC Symbol)
Synonyms	CLECSF10, dectin-2
Description	C-type lectin domain family 6, member A (HGNC Symbol)
Entrez gene summary	Like dectin-1 (CLEC7A; MIM 606264), CLEC6A, or dectin-2, is a type II membrane receptor with an extracellular C-type lectin-like domain fold. However, unlike dectin-1, dectin-2 lacks an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain (Kanazawa et al., 2004 [PubMed 15175046]).[supplied by OMIM, Nov 2010]
Chromosome	12
Cytoband	p13.31
Chromosome location (bp)	8455926 - 8478330
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000205846 (version 83.38)
Entrez gene	93978
UniProt	Q6EIG7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6EIG7
Antibodypedia	CLEC6A antibodies

PROTEIN BROWSER

CLEC6A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CLEC6A-001 ENSP00000371505 ENST00000382073	Q6EIG7 [Direct mapping] C-type lectin domain family 6 member A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0002223 [stimulatory C-type lectin receptor signaling pathway] GO:0002250 [adaptive immune response] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030246 [carbohydrate binding] GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling] GO:0045087 [innate immune response] GO:0050715 [positive regulation of cytokine secretion] GO:0050832 [defense response to fungus] Show all	209 aa 24 kDa	No	1