Expression of HACD2 in cancer - Summary - The Human Protein Atlas

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HACD2

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

3-hydroxyacyl-CoA dehydratase 2

Protein class

Enzymes, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

CAB019282

GENE INFORMATION
Gene name	HACD2 (HGNC Symbol)
Synonyms	PTPLB
Description	3-hydroxyacyl-CoA dehydratase 2 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q21.1
Chromosome location (bp)	123490820 - 123585185
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000206527 (version 83.38)
Entrez gene	201562
UniProt	Q6Y1H2 (UniProt - Evidence at protein level)
neXtProt	NX_Q6Y1H2
Antibodypedia	HACD2 antibodies

PROTEIN BROWSER

HACD2-001	HACD2-003	HACD2-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HACD2-001 ENSP00000373153 ENST00000383657	Q6Y1H2 [Direct mapping] Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 Show all	Enzymes ENZYME proteins Lyases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0018812 [3-hydroxyacyl-CoA dehydratase activity] GO:0019432 [triglyceride biosynthetic process] GO:0019899 [enzyme binding] GO:0030148 [sphingolipid biosynthetic process] GO:0030497 [fatty acid elongation] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0042761 [very long-chain fatty acid biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] Show all	254 aa 28.4 kDa	No	6
HACD2-003 ENSP00000417567 ENST00000493515	H7C4K8 [Direct mapping] Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	61 aa 6.9 kDa	No	2
HACD2-005 ENSP00000419237 ENST00000469317	C9JWG1 [Direct mapping] Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	98 aa 11.4 kDa	Yes	2

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.