Expression of SACM1L in cancer - Summary

CANCER ATLAS

Gene description

SAC1 suppressor of actin mutations 1-like (yeast)

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA039573

GENE INFORMATION
Gene name	SACM1L (HGNC Symbol)
Synonyms	KIAA0851, SAC1
Description	SAC1 suppressor of actin mutations 1-like (yeast) (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	p21.31
Chromosome location (bp)	45689056 - 45745424
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000211456 (version 83.38)
Entrez gene	22908
UniProt	Q9NTJ5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NTJ5
Antibodypedia	SACM1L antibodies

PROTEIN BROWSER

SACM1L-001	SACM1L-002	SACM1L-009	SACM1L-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SACM1L-001 ENSP00000373713 ENST00000389061	Q9NTJ5 [Direct mapping] Phosphatidylinositide phosphatase SAC1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005794 [Golgi apparatus] GO:0006644 [phospholipid metabolic process] GO:0006661 [phosphatidylinositol biosynthetic process] GO:0008150 [biological_process] GO:0016791 [phosphatase activity] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0032281 [AMPA glutamate receptor complex] GO:0034593 [phosphatidylinositol bisphosphate phosphatase activity] GO:0042578 [phosphoric ester hydrolase activity] GO:0043812 [phosphatidylinositol-4-phosphate phosphatase activity] GO:0044281 [small molecule metabolic process] GO:0046856 [phosphatidylinositol dephosphorylation] Show all	587 aa 67 kDa	No	3
SACM1L-002 ENSP00000396387 ENST00000418611	E9PGZ4 [Direct mapping] Phosphatidylinositide phosphatase SAC1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0042578 [phosphoric ester hydrolase activity] Show all	484 aa 55.6 kDa	No	2
SACM1L-009 ENSP00000411966 ENST00000438671	C9J3E3 [Direct mapping] Phosphatidylinositide phosphatase SAC1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0042578 [phosphoric ester hydrolase activity] Show all	112 aa 13.6 kDa	No	0
SACM1L-012 ENSP00000412883 ENST00000433336	C9JV50 [Direct mapping] Phosphatidylinositide phosphatase SAC1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0042578 [phosphoric ester hydrolase activity] Show all	187 aa 21.4 kDa	No	0