Cell atlas - TAS2R50 - The Human Protein Atlas

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TAS2R50

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	TAS2R50
Gene description	Taste receptor, type 2, member 50
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	TAS2R50 (HGNC Symbol)
Synonyms	T2R51
Description	Taste receptor, type 2, member 50 (HGNC Symbol)
Entrez gene summary	TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). See also TAS2R10 (MIM 604791).[supplied by OMIM, Mar 2008]
Chromosome	12
Cytoband	p13.2
Chromosome location (bp)	10985913 - 10986912
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000212126 (version 83.38)
Entrez gene	259296
UniProt	P59544 (UniProt - Evidence at transcript level)
neXtProt	NX_P59544
Antibodypedia	TAS2R50 antibodies

PROTEIN BROWSER

TAS2R50-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TAS2R50-001 ENSP00000424040 ENST00000506868	P59544 [Direct mapping] Taste receptor type 2 member 50 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Family T2R receptors (taste receptor GPCRs) Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0001580 [detection of chemical stimulus involved in sensory perception of bitter taste] GO:0004930 [G-protein coupled receptor activity] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0033038 [bitter taste receptor activity] GO:0050909 [sensory perception of taste] Show all	299 aa 34.6 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.