Expression of CRIP1 in cancer - Summary

CANCER ATLAS

Gene description

Cysteine-rich protein 1 (intestinal)

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA042462

GENE INFORMATION
Gene name	CRIP1 (HGNC Symbol)
Synonyms	CRIP
Description	Cysteine-rich protein 1 (intestinal) (HGNC Symbol)
Entrez gene summary	Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991 [PubMed 1946385]).[supplied by OMIM, Mar 2008]
Chromosome	14
Cytoband	q32.33
Chromosome location (bp)	105486317 - 105488947
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000213145 (version 83.38)
Entrez gene	1396
UniProt	P50238 (UniProt - Evidence at protein level)
neXtProt	NX_P50238
Antibodypedia	CRIP1 antibodies

PROTEIN BROWSER

CRIP1-001	CRIP1-002	CRIP1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CRIP1-001 ENSP00000386340 ENST00000409393	P50238 [Direct mapping] Cysteine-rich protein 1 Show all	Predicted intracellular proteins Plasma proteins Show all	GO:0003680 [AT DNA binding] GO:0005737 [cytoplasm] GO:0006955 [immune response] GO:0007507 [heart development] GO:0008270 [zinc ion binding] GO:0008283 [cell proliferation] GO:0008301 [DNA binding, bending] GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage] GO:0010033 [response to organic substance] GO:0010043 [response to zinc ion] GO:0010468 [regulation of gene expression] GO:0042277 [peptide binding] GO:0060741 [prostate gland stromal morphogenesis] GO:0071236 [cellular response to antibiotic] GO:0071493 [cellular response to UV-B] Show all	77 aa 8.5 kDa	No	0
CRIP1-002 ENSP00000376315 ENST00000392531	P50238 [Direct mapping] Cysteine-rich protein 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0003680 [AT DNA binding] GO:0005737 [cytoplasm] GO:0006955 [immune response] GO:0007507 [heart development] GO:0008270 [zinc ion binding] GO:0008283 [cell proliferation] GO:0008301 [DNA binding, bending] GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage] GO:0010033 [response to organic substance] GO:0010043 [response to zinc ion] GO:0010468 [regulation of gene expression] GO:0042277 [peptide binding] GO:0060741 [prostate gland stromal morphogenesis] GO:0071236 [cellular response to antibiotic] GO:0071493 [cellular response to UV-B] Show all	77 aa 8.5 kDa	No	0
CRIP1-006 ENSP00000332449 ENST00000330233	P50238 [Direct mapping] Cysteine-rich protein 1 Show all	Predicted intracellular proteins Plasma proteins Show all	GO:0003680 [AT DNA binding] GO:0005737 [cytoplasm] GO:0006955 [immune response] GO:0007507 [heart development] GO:0008270 [zinc ion binding] GO:0008283 [cell proliferation] GO:0008301 [DNA binding, bending] GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage] GO:0010033 [response to organic substance] GO:0010043 [response to zinc ion] GO:0010468 [regulation of gene expression] GO:0042277 [peptide binding] GO:0060741 [prostate gland stromal morphogenesis] GO:0071236 [cellular response to antibiotic] GO:0071493 [cellular response to UV-B] Show all	77 aa 8.5 kDa	No	0