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GIMAP1

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GENERAL INFORMATION

Gene name

 GIMAP1

Gene description

 GTPase, IMAP family member 1

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the endoplasmic reticulum. Caution: Based on antibodies targeting proteins from multiple genes.

RNA cell category

 Group enriched (HUVEC TERT2, MOLT-4, TIME)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Endoplasmic reticulum (supported)

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
HPA053441
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (HUVEC TERT2, MOLT-4, TIME)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the endoplasmic reticulum. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

 Endoplasmic reticulum (supported)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA053441 HUVEC TERT2 Endoplasmic reticulum
HPA053441 U-2 OS No staining    
HPA053441 U-251 MG No staining    

GENE INFORMATION

Gene name

 GIMAP1 (HGNC Symbol)

Synonyms

 HIMAP1, IAN2, IMAP1, IMAP38

Description

 GTPase, IMAP family member 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene is thought to be involved in the differentiation of T helper (Th) cells of the Th1 lineage, and the related mouse gene has been shown to be critical for the development of mature B and T lymphocytes. Read-through transcription exists between this gene and the downstream GIMAP5 (GTPase, IMAP family member 5) gene. [provided by RefSeq, Dec 2010]

Chromosome

 7

Cytoband

 q36.1

Chromosome location (bp)

 150716557 - 150724284

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000213203 (version 83.38)

Entrez gene

 170575

UniProt

 Q8WWP7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WWP7

Antibodypedia

 GIMAP1 antibodies

PROTEIN BROWSER
GIMAP1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GIMAP1-001
ENSP00000302833
ENST00000307194
Q8WWP7 [Direct mapping]
GTPase IMAP family member 1
A0A090N8Z4 [Target identity:100%; Query identity:100%]
Immunity associated protein 1
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000139 [Golgi membrane]
GO:0005525 [GTP binding]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0016021 [integral component of membrane]
GO:0030183 [B cell differentiation]
GO:0030217 [T cell differentiation]
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 306 aa
34.4 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.