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ARHGAP19

CANCER ATLAS

Gene description

 Rho GTPase activating protein 19

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA043231

GENE INFORMATION

Gene name

 ARHGAP19 (HGNC Symbol)

Synonyms

 FLJ00194, MGC14258

Description

 Rho GTPase activating protein 19 (HGNC Symbol)

Entrez gene summary

 Members of the ARHGAP family, such as ARHGAP19, encode negative regulators of Rho GTPases (see RHOA; MIM 165390), which are involved in cell migration, proliferation, and differentiation, actin remodeling, and G1 cell cycle progression (Lv et al., 2007 [PubMed 17454002]).[supplied by OMIM, Mar 2008]

Chromosome

 10

Cytoband

 q24.1

Chromosome location (bp)

 97222173 - 97292673

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000213390 (version 83.38)

Entrez gene

 84986

UniProt

 Q14CB8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q14CB8

Antibodypedia

 ARHGAP19 antibodies

PROTEIN BROWSER
ARHGAP19-002
ARHGAP19-003
ARHGAP19-006
ARHGAP19-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARHGAP19-002
ENSP00000360066
ENST00000371027
Q14CB8 [Direct mapping]
Rho GTPase-activating protein 19
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0043547 [positive regulation of GTPase activity]
GO:0051056 [regulation of small GTPase mediated signal transduction]
Show all
 485 aa
54.9 kDa 		No 0
ARHGAP19-003
ENSP00000351333
ENST00000358531
Q14CB8 [Direct mapping]
Rho GTPase-activating protein 19
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0043547 [positive regulation of GTPase activity]
GO:0051056 [regulation of small GTPase mediated signal transduction]
Show all
 494 aa
55.8 kDa 		No 0
ARHGAP19-006
ENSP00000473667
ENST00000466484
R4GNI4 [Direct mapping]
Rho GTPase-activating protein 19
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007165 [signal transduction]
Show all
 197 aa
22.2 kDa 		No 0
ARHGAP19-201
ENSP00000351058
ENST00000358308
Q14CB8 [Direct mapping]
Rho GTPase-activating protein 19
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0043547 [positive regulation of GTPase activity]
GO:0051056 [regulation of small GTPase mediated signal transduction]
Show all
 465 aa
52.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.