Expression of TMX2 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Thioredoxin-related transmembrane protein 2

Protein class

Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA040282	HPA063763

GENE INFORMATION
Gene name	TMX2 (HGNC Symbol)
Synonyms	PDIA12, TXNDC14
Description	Thioredoxin-related transmembrane protein 2 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q12.1
Chromosome location (bp)	57712600 - 57740973
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000213593 (version 83.38)
Entrez gene	51075
UniProt	Q9Y320 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y320
Antibodypedia	TMX2 antibodies

PROTEIN BROWSER

TMX2-001	TMX2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMX2-001 ENSP00000367562 ENST00000378312	Q9Y320 [Direct mapping] Thioredoxin-related transmembrane protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005623 [cell] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0045454 [cell redox homeostasis] Show all	258 aa 29.6 kDa	Yes	0
TMX2-002 ENSP00000278422 ENST00000278422	Q9Y320 [Direct mapping] Thioredoxin-related transmembrane protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005623 [cell] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0045454 [cell redox homeostasis] Show all	296 aa 34 kDa	Yes	2