Tissue expression of PLIN5 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PLIN5
Gene description	Perilipin 5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (ovary, adipose tissue)
GTEx:	Expressed in all
FANTOM5:	Tissue enhanced (salivary gland)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (ovary, adipose tissue)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (salivary gland)

GENE INFORMATION
Gene name	PLIN5 (HGNC Symbol)
Synonyms	LSDA5, LSDP5, MLDP, OXPAT
Description	Perilipin 5 (HGNC Symbol)
Entrez gene summary	Members of the perilipin family, such as PLIN5, coat intracellular lipid storage droplets and protect them from lipolytic degradation (Dalen et al., 2007 [PubMed 17234449]).[supplied by OMIM, Feb 2010]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	4522531 - 4535224
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000214456 (version 83.38)
Entrez gene	440503
UniProt	Q00G26 (UniProt - Evidence at protein level)
neXtProt	NX_Q00G26
Antibodypedia	PLIN5 antibodies

PROTEIN BROWSER

PLIN5-001	PLIN5-004	PLIN5-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PLIN5-001 ENSP00000371272 ENST00000381848	Q00G26 [Direct mapping] Perilipin-5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005811 [lipid particle] GO:0005829 [cytosol] GO:0010867 [positive regulation of triglyceride biosynthetic process] GO:0010884 [positive regulation of lipid storage] GO:0010890 [positive regulation of sequestering of triglyceride] GO:0010897 [negative regulation of triglyceride catabolic process] GO:0019915 [lipid storage] GO:0031999 [negative regulation of fatty acid beta-oxidation] GO:0032000 [positive regulation of fatty acid beta-oxidation] GO:0034389 [lipid particle organization] GO:0035359 [negative regulation of peroxisome proliferator activated receptor signaling pathway] GO:0035473 [lipase binding] GO:0042802 [identical protein binding] GO:0050995 [negative regulation of lipid catabolic process] GO:0051646 [mitochondrion localization] GO:0060192 [negative regulation of lipase activity] GO:0060193 [positive regulation of lipase activity] GO:2000378 [negative regulation of reactive oxygen species metabolic process] Show all	463 aa 50.8 kDa	No	0
PLIN5-004 ENSP00000464926 ENST00000592610	K7EIX1 [Direct mapping] Perilipin-5 Show all	Predicted intracellular proteins Show all		58 aa 6.2 kDa	No	0
PLIN5-006 ENSP00000468027 ENST00000586133	K7EIX1 [Direct mapping] Perilipin-5 Show all	Predicted intracellular proteins Show all		58 aa 6.2 kDa	No	0