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Several cases of most cancer tissues displayed moderate cytoplasmic staining with additional nuclear positivity in a few cases. A few testicular seminomas, squamous cell carcinoma of skin, adenocarcinoma of lung and hepatocellular carcinoma of liver were strongly stained. Remaining cancer cells were weakly stained or negative.
Several cases of skin and urothelial cancers along with few cases of melanomas, cervical and testicular cancers displayed moderate cytoplasmic and/or membranous staining. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
NEURL4 (HGNC Symbol)
Synonyms
KIAA1787
Description
Neuralized E3 ubiquitin protein ligase 4 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is predicted and it includes two isoforms resulting from two alternatively spliced transcript variants. [provided by RefSeq, Jul 2008]