Expression of GRID2IP in cancer - Summary

CANCER ATLAS

Gene description

Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Renal cancer

STAINING SUMMARY

HPA045381

GENE INFORMATION
Gene name	GRID2IP
Synonyms
Description	Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein (HGNC Symbol)
Entrez gene summary	Glutamate receptor delta-2 (GRID2; MIM 602368) is predominantly expressed at parallel fiber-Purkinje cell postsynapses and plays crucial roles in synaptogenesis and synaptic plasticity. GRID2IP1 interacts with GRID2 and may control GRID2 signaling in Purkinje cells (Matsuda et al., 2006 [PubMed 16835239]).[supplied by OMIM, Mar 2008]
Chromosome	7
Cytoband	p22.1
Chromosome location (bp)	6497462 - 6551436
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000215045 (version 83.38)
Entrez gene	392862
UniProt	A4D2P6 (UniProt - Inferred from homology)
neXtProt	NX_A4D2P6
Antibodypedia	GRID2IP antibodies

PROTEIN BROWSER

GRID2IP-001	GRID2IP-003	GRID2IP-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GRID2IP-001 ENSP00000397351 ENST00000457091	A4D2P6 [Direct mapping] Delphilin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0030054 [cell junction] GO:0043197 [dendritic spine] GO:0045202 [synapse] GO:0045211 [postsynaptic membrane] GO:0060292 [long term synaptic depression] Show all	1211 aa 132.3 kDa	No	0
GRID2IP-003 ENSP00000397887 ENST00000452113	C9J5F6 [Direct mapping] Delphilin Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	1020 aa 111.9 kDa	No	0
GRID2IP-004 ENSP00000408364 ENST00000435185	C9JNS8 [Direct mapping] Delphilin Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	1027 aa 112.9 kDa	No	0