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Malignant tissues showed weak to moderate cytoplasmic and occasional nucleolar staining. Several cases of hepatocellular carcinomas along with occasional cases of stomach, colorectal and pancreatic cancers displayed strong positivity. Several cases of malignant gliomas, carcinoids and lymphomas were negative.
GENE INFORMATION
Gene name
RPL17-C18orf32
Synonyms
Description
RPL17-C18orf32 readthrough (HGNC Symbol)
Entrez gene summary
This locus represents naturally occurring read-through transcription between the neighboring RPL17 (ribosomal protein L17) and C18orf32 (chromosome 18 open reading frame 32) genes. Alternative splicing results in multiple transcript variants. The encoded isoforms share sequence identity with the RPL17 protein, but they include frameshifted C-terminal regions derived from the downstream gene exons. [provided by RefSeq, Dec 2010]