Tissue expression of SKOR2 - Summary - The Human Protein Atlas

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SKOR2

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SKOR2
Gene description	SKI family transcriptional corepressor 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Not detected
GTEx:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. No RNA expression data detected and pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA046206
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Not detected
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	SKOR2 (HGNC Symbol)
Synonyms	CORL2, Fussel-18, FUSSEL18
Description	SKI family transcriptional corepressor 2 (HGNC Symbol)
Entrez gene summary
Chromosome	18
Cytoband	q21.1
Chromosome location (bp)	47212089 - 47249183
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000215474 (version 83.38)
Entrez gene	652991
UniProt	Q2VWA4 (UniProt - Evidence at protein level)
neXtProt	NX_Q2VWA4
Antibodypedia	SKOR2 antibodies

PROTEIN BROWSER

SKOR2-001	SKOR2-002	SKOR2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SKOR2-001 ENSP00000383255 ENST00000400404	Q2VWA4 [Direct mapping] SKI family transcriptional corepressor 2 Show all	Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] GO:0046332 [SMAD binding] Show all	296 aa 33.4 kDa	No	0
SKOR2-002 ENSP00000414750 ENST00000425639	Q2VWA4 [Direct mapping] SKI family transcriptional corepressor 2 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] GO:0046332 [SMAD binding] Show all	1001 aa 104.2 kDa	No	0
SKOR2-201 ENSP00000483333 ENST00000620245	A0A087X0E6 [Direct mapping] SKI family transcriptional corepressor 2 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003682 [chromatin binding] GO:0003714 [transcription corepressor activity] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0021587 [cerebellum morphogenesis] GO:0021702 [cerebellar Purkinje cell differentiation] GO:0021936 [regulation of cerebellar granule cell precursor proliferation] GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] GO:0030514 [negative regulation of BMP signaling pathway] GO:0042826 [histone deacetylase binding] GO:0045880 [positive regulation of smoothened signaling pathway] GO:0046332 [SMAD binding] GO:0048468 [cell development] GO:0048814 [regulation of dendrite morphogenesis] Show all	1015 aa 105.8 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.