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Most malignant cells were negative. Few cases of malignant carcinoids, papillary adenocarcinoma of thyroid and lung cancers showed moderate cytoplasmic positivity.
GENE INFORMATION
Gene name
DEFB116 (HGNC Symbol)
Synonyms
DEFB-16
Description
Defensin, beta 116 (HGNC Symbol)
Entrez gene summary
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. [provided by RefSeq, Oct 2014]
