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Hepatocellular and thyroid cancer exhibited moderate to strong cytoplasmic and nuclear positivity. A few cases of breast and ovarian malignancies showed moderate positivity. Remaining malignant tissues were weakly stained or negative.
GENE INFORMATION
Gene name
DEFB115 (HGNC Symbol)
Synonyms
DEFB-15
Description
Defensin, beta 115 (HGNC Symbol)
Entrez gene summary
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. [provided by RefSeq, Oct 2014]
