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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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RPTN
  • TISSUE

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  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Repetin

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY

HPA030483
HPA030485

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Cancer tissues were mainly negative. A subset of cancer cells in a few cases of urothelial cancer displayed strong cytoplasmic and nuclear positivity.

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Several breast, colorectal, pancreas, cervical, ovarian along with few urothelial and stomach cancers showed weak to moderate cytoplasmic positivity. Pancreatic and colorectal cancers exhibited additional membranous staining. Remaining cancer tissues were generally negative.

GENE INFORMATION

Gene name

RPTN (HGNC Symbol)

Synonyms

FLJ39117

Description

Repetin (HGNC Symbol)

Entrez gene summary

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

152153595 - 152159228

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000215853 (version 83.38)

Entrez gene

126638

UniProt

Q6XPR3 (UniProt - Evidence at protein level)

neXtProt

NX_Q6XPR3

Antibodypedia

RPTN antibodies

PROTEIN BROWSER

RPTN-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPTN-001
ENSP00000317895
ENST00000316073
Q6XPR3 [Direct mapping]
Repetin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001533 [cornified envelope]
GO:0005509 [calcium ion binding]
GO:0005578 [proteinaceous extracellular matrix]
Show all
784 aa
90.7 kDa
No 0

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The Human Protein Atlas project is funded
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