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Malignant tissues showed weak to moderate nuclear membranous staining. Several cases of papillary adenocarcinomas of thyroid, squamous cell carcinomas of cervix along with a few cases of urothelial and pancreatic cancers displayed strong positivity. Several cases of malignant lymphomas and prostate cancers were negative.
P0C6A0 [Direct mapping] GATA-type zinc finger protein 1
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Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014)
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001085 [RNA polymerase II transcription factor binding] GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0003682 [chromatin binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007275 [multicellular organismal development] GO:0007283 [spermatogenesis] GO:0008270 [zinc ion binding] GO:0030154 [cell differentiation] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048599 [oocyte development]
B5MCP8 [Direct mapping] GATA-type zinc finger protein 1
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Predicted intracellular proteins
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GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0043565 [sequence-specific DNA binding]
