Tissue expression of ELFN1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ELFN1
Gene description	Extracellular leucine-rich repeat and fibronectin type III domain containing 1
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (liver, cerebral cortex)
GTEx:	Mixed

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (liver, cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	ELFN1 (HGNC Symbol)
Synonyms	PPP1R28
Description	Extracellular leucine-rich repeat and fibronectin type III domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	p22.3
Chromosome location (bp)	1688119 - 1747954
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000225968 (version 83.38)
Entrez gene	392617
UniProt	P0C7U0 (UniProt - Evidence at protein level)
neXtProt	NX_P0C7U0
Antibodypedia	ELFN1 antibodies

PROTEIN BROWSER

ELFN1-001	ELFN1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ELFN1-001 ENSP00000456548 ENST00000424383	P0C7U0 [Direct mapping] Protein ELFN1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004864 [protein phosphatase inhibitor activity] GO:0005515 [protein binding] GO:0010923 [negative regulation of phosphatase activity] GO:0016021 [integral component of membrane] GO:0019902 [phosphatase binding] GO:0030425 [dendrite] GO:0050808 [synapse organization] GO:0060076 [excitatory synapse] GO:0070062 [extracellular exosome] Show all	828 aa 90.5 kDa	Yes	1
ELFN1-201 ENSP00000457193 ENST00000561626	P0C7U0 [Direct mapping] Protein ELFN1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004864 [protein phosphatase inhibitor activity] GO:0005515 [protein binding] GO:0010923 [negative regulation of phosphatase activity] GO:0016021 [integral component of membrane] GO:0019902 [phosphatase binding] GO:0030425 [dendrite] GO:0050808 [synapse organization] GO:0060076 [excitatory synapse] GO:0070062 [extracellular exosome] Show all	828 aa 90.5 kDa	Yes	1