Cell atlas - TAS2R46 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

TAS2R46

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	TAS2R46
Gene description	Taste receptor, type 2, member 46
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	TAS2R46 (HGNC Symbol)
Synonyms	T2R54
Description	Taste receptor, type 2, member 46 (HGNC Symbol)
Entrez gene summary	TAS2R46 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.[supplied by OMIM, Sep 2009]
Chromosome	12
Cytoband	p13.2
Chromosome location (bp)	11061365 - 11062294
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000226761 (version 83.38)
Entrez gene	259292
UniProt	P59540 (UniProt - Evidence at transcript level)
neXtProt	NX_P59540
Antibodypedia	TAS2R46 antibodies

PROTEIN BROWSER

TAS2R46-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TAS2R46-001 ENSP00000436450 ENST00000533467	P59540 [Direct mapping] Taste receptor type 2 member 46 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Family T2R receptors (taste receptor GPCRs) Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0001580 [detection of chemical stimulus involved in sensory perception of bitter taste] GO:0004930 [G-protein coupled receptor activity] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0033038 [bitter taste receptor activity] GO:0050909 [sensory perception of taste] GO:0060170 [ciliary membrane] Show all	309 aa 35.5 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.