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Moderate nuclear staining was observed in a case of seminoma of testis. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
RBMY1J
Synonyms
Description
RNA binding motif protein, Y-linked, family 1, member J (HGNC Symbol)
Entrez gene summary
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq, Jul 2008]