Expression of AKR1B15 in cancer - Summary

CANCER ATLAS

Gene description

Aldo-keto reductase family 1, member B15

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA020280

GENE INFORMATION
Gene name	AKR1B15
Synonyms
Description	Aldo-keto reductase family 1, member B15 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q33
Chromosome location (bp)	134549136 - 134579875
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000227471 (version 83.38)
Entrez gene	441282
UniProt	C9JRZ8 (UniProt - Evidence at protein level)
neXtProt	NX_C9JRZ8
Antibodypedia	AKR1B15 antibodies

PROTEIN BROWSER

AKR1B15-001	AKR1B15-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AKR1B15-001 ENSP00000389289 ENST00000457545	C9JRZ8 [Direct mapping] Aldo-keto reductase family 1 member B15 Show all	Enzymes ENZYME proteins Oxidoreductases Predicted intracellular proteins Show all	GO:0004303 [estradiol 17-beta-dehydrogenase activity] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0005829 [cytosol] GO:0006703 [estrogen biosynthetic process] GO:0008202 [steroid metabolic process] GO:0016491 [oxidoreductase activity] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0044281 [small molecule metabolic process] GO:0055114 [oxidation-reduction process] Show all	344 aa 39.5 kDa	No	0
AKR1B15-201 ENSP00000397009 ENST00000423958	C9JRZ8 [Direct mapping] Aldo-keto reductase family 1 member B15 Show all	Enzymes ENZYME proteins Oxidoreductases Predicted intracellular proteins Show all	GO:0004303 [estradiol 17-beta-dehydrogenase activity] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0005829 [cytosol] GO:0006703 [estrogen biosynthetic process] GO:0008202 [steroid metabolic process] GO:0016491 [oxidoreductase activity] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0044281 [small molecule metabolic process] GO:0055114 [oxidation-reduction process] Show all	344 aa 39.5 kDa	No	0