Expression of SPINK8 in cancer - Summary

CANCER ATLAS

Gene description

Serine peptidase inhibitor, Kazal type 8 (putative)

Protein class

Predicted secreted proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA053151

GENE INFORMATION
Gene name	SPINK8
Synonyms
Description	Serine peptidase inhibitor, Kazal type 8 (putative) (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	p21.31
Chromosome location (bp)	48306842 - 48328341
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000229453 (version 83.38)
Entrez gene	646424
UniProt	P0C7L1 (UniProt - Inferred from homology)
neXtProt	NX_P0C7L1
Antibodypedia	SPINK8 antibodies

PROTEIN BROWSER

SPINK8-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPINK8-001 ENSP00000407497 ENST00000434006	P0C7L1 [Direct mapping] Serine protease inhibitor Kazal-type 8 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Show all	GO:0004867 [serine-type endopeptidase inhibitor activity] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0010951 [negative regulation of endopeptidase activity] Show all	97 aa 10.8 kDa	Yes	0