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PRPS1L1

GENERAL INFORMATION

Gene name

 PRPS1L1

Gene description

 Phosphoribosyl pyrophosphate synthetase 1-like 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

 Evidence at transcript level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 PRPS1L1 (HGNC Symbol)

Synonyms

 PRPS3, PRPSL

Description

 Phosphoribosyl pyrophosphate synthetase 1-like 1 (HGNC Symbol)

Entrez gene summary

 This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq, Jul 2008]

Chromosome

 7

Cytoband

 p21.1

Chromosome location (bp)

 18026774 - 18027863

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000229937 (version 83.38)

Entrez gene

 221823

UniProt

neXtProt

Antibodypedia

 PRPS1L1 antibodies

PROTEIN BROWSER
PRPS1L1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PRPS1L1-001
ENSP00000424595
ENST00000506618
A0A0B4J207 [Direct mapping]
Ribose-phosphate pyrophosphokinase 3
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Predicted intracellular proteins
Show all
GO:0000287 [magnesium ion binding]
GO:0004749 [ribose phosphate diphosphokinase activity]
GO:0008584 [male gonad development]
GO:0009156 [ribonucleoside monophosphate biosynthetic process]
GO:0009165 [nucleotide biosynthetic process]
GO:0044249 [cellular biosynthetic process]
Show all
 318 aa
34.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.