Tissue expression of MBD3L2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	MBD3L2
Gene description	Methyl-CpG binding domain protein 3-like 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Not detected
GTEx:	Not detected

Protein evidence

Evidence at transcript level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA051259
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Not detected
GTEx dataset Organ Expression Alphabetical RNA tissue category: Not detected

GENE INFORMATION
Gene name	MBD3L2
Synonyms
Description	Methyl-CpG binding domain protein 3-like 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein has been found in germ cell tumors and some somatic tissues. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	7049321 - 7051735
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000230522 (version 83.38)
Entrez gene	125997
UniProt	Q8NHZ7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NHZ7
Antibodypedia	MBD3L2 antibodies

PROTEIN BROWSER

MBD3L2-001	MBD3L2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MBD3L2-001 ENSP00000370800 ENST00000381393	Q8NHZ7 [Direct mapping] Methyl-CpG-binding domain protein 3-like 2 Show all	Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0005634 [nucleus] GO:0006346 [methylation-dependent chromatin silencing] GO:0008327 [methyl-CpG binding] Show all	208 aa 23 kDa	No	0
MBD3L2-201 ENSP00000480390 ENST00000616171	A0A087WWP0 [Direct mapping] Methyl-CpG-binding domain protein 3-like 2 Show all	Predicted intracellular proteins Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0005634 [nucleus] GO:0006346 [methylation-dependent chromatin silencing] GO:0008327 [methyl-CpG binding] Show all	204 aa 22.7 kDa	No	0