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RPS18

CANCER ATLAS

Gene description

 Ribosomal protein S18

Protein class

 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA050159

GENE INFORMATION

Gene name

 RPS18 (HGNC Symbol)

Synonyms

 D6S218E, HKE3, KE-3, KE3, S18

Description

 Ribosomal protein S18 (HGNC Symbol)

Entrez gene summary

 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Chromosome

 6

Cytoband

 p21.32

Chromosome location (bp)

 33272010 - 33276510

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000231500 (version 83.38)

Entrez gene

 6222

UniProt

 P62269 (UniProt - Evidence at protein level)

neXtProt

 NX_P62269

Antibodypedia

 RPS18 antibodies

PROTEIN BROWSER
RPS18-001
RPS18-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPS18-001
ENSP00000393241
ENST00000439602
P62269 [Direct mapping]
40S ribosomal protein S18
Show all
Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015935 [small ribosomal subunit]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0019843 [rRNA binding]
GO:0022627 [cytosolic small ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0070062 [extracellular exosome]
Show all
 152 aa
17.7 kDa 		No 0
RPS18-002
ENSP00000434837
ENST00000474973
J3JS69 [Direct mapping]
40S ribosomal protein S18; HCG1777176, isoform CRA_a; Ribosomal protein S18; Ribosomal protein S18, isoform CRA_a
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005581 [collagen trimer]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
 82 aa
9.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.