P01375 [Direct mapping]
Tumor necrosis factor Tumor necrosis factor, membrane form Intracellular domain 1 Intracellular domain 2 C-domain 1 C-domain 2 Tumor necrosis factor, soluble form
Q5STB3 [Target identity:100%; Query identity:100%]
TNFA protein; Tumor necrosis factor; Tumor necrosis factor (TNF superfamily, member 2); Tumor necrosis factor-alpha; cDNA, FLJ95875, Homo sapiens tumor necrosis factor (TNF superfamily, member 2)(TNF), mRNA

GO:0000060 [protein import into nucleus, translocation]
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000185 [activation of MAPKKK activity]
GO:0000187 [activation of MAPK activity]
GO:0001819 [positive regulation of cytokine production]
GO:0001891 [phagocytic cup]
GO:0001932 [regulation of protein phosphorylation]
GO:0001934 [positive regulation of protein phosphorylation]
GO:0002020 [protease binding]
GO:0002439 [chronic inflammatory response to antigenic stimulus]
GO:0002740 [negative regulation of cytokine secretion involved in immune response]
GO:0002876 [positive regulation of chronic inflammatory response to antigenic stimulus]
GO:0002925 [positive regulation of humoral immune response mediated by circulating immunoglobulin]
GO:0005125 [cytokine activity]
GO:0005164 [tumor necrosis factor receptor binding]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005622 [intracellular]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006006 [glucose metabolic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0006927 [transformed cell apoptotic process]
GO:0006952 [defense response]
GO:0006954 [inflammatory response]
GO:0006955 [immune response]
GO:0006959 [humoral immune response]
GO:0007166 [cell surface receptor signaling pathway]
GO:0007249 [I-kappaB kinase/NF-kappaB signaling]
GO:0007254 [JNK cascade]
GO:0007275 [multicellular organismal development]
GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors]
GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage]
GO:0009615 [response to virus]
GO:0009651 [response to salt stress]
GO:0009887 [organ morphogenesis]
GO:0009897 [external side of plasma membrane]
GO:0009986 [cell surface]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010693 [negative regulation of alkaline phosphatase activity]
GO:0010803 [regulation of tumor necrosis factor-mediated signaling pathway]
GO:0010888 [negative regulation of lipid storage]
GO:0016020 [membrane]
GO:0030198 [extracellular matrix organization]
GO:0030316 [osteoclast differentiation]
GO:0030730 [sequestering of triglyceride]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0031334 [positive regulation of protein complex assembly]
GO:0031622 [positive regulation of fever generation]
GO:0031663 [lipopolysaccharide-mediated signaling pathway]
GO:0032715 [negative regulation of interleukin-6 production]
GO:0032722 [positive regulation of chemokine production]
GO:0032729 [positive regulation of interferon-gamma production]
GO:0032755 [positive regulation of interleukin-6 production]
GO:0032757 [positive regulation of interleukin-8 production]
GO:0032800 [receptor biosynthetic process]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0033209 [tumor necrosis factor-mediated signaling pathway]
GO:0034116 [positive regulation of heterotypic cell-cell adhesion]
GO:0035509 [negative regulation of myosin-light-chain-phosphatase activity]
GO:0042127 [regulation of cell proliferation]
GO:0042346 [positive regulation of NF-kappaB import into nucleus]
GO:0042742 [defense response to bacterium]
GO:0042802 [identical protein binding]
GO:0043065 [positive regulation of apoptotic process]
GO:0043068 [positive regulation of programmed cell death]
GO:0043122 [regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043242 [negative regulation of protein complex disassembly]
GO:0043243 [positive regulation of protein complex disassembly]
GO:0043280 [positive regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043406 [positive regulation of MAP kinase activity]
GO:0043491 [protein kinase B signaling]
GO:0043507 [positive regulation of JUN kinase activity]
GO:0044130 [negative regulation of growth of symbiont in host]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045071 [negative regulation of viral genome replication]
GO:0045080 [positive regulation of chemokine biosynthetic process]
GO:0045121 [membrane raft]
GO:0045123 [cellular extravasation]
GO:0045416 [positive regulation of interleukin-8 biosynthetic process]
GO:0045429 [positive regulation of nitric oxide biosynthetic process]
GO:0045599 [negative regulation of fat cell differentiation]
GO:0045662 [negative regulation of myoblast differentiation]
GO:0045668 [negative regulation of osteoblast differentiation]
GO:0045670 [regulation of osteoclast differentiation]
GO:0045672 [positive regulation of osteoclast differentiation]
GO:0045785 [positive regulation of cell adhesion]
GO:0045860 [positive regulation of protein kinase activity]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0045994 [positive regulation of translational initiation by iron]
GO:0046325 [negative regulation of glucose import]
GO:0046330 [positive regulation of JNK cascade]
GO:0048566 [embryonic digestive tract development]
GO:0048661 [positive regulation of smooth muscle cell proliferation]
GO:0050708 [regulation of protein secretion]
GO:0050715 [positive regulation of cytokine secretion]
GO:0050766 [positive regulation of phagocytosis]
GO:0050796 [regulation of insulin secretion]
GO:0050830 [defense response to Gram-positive bacterium]
GO:0050900 [leukocyte migration]
GO:0050901 [leukocyte tethering or rolling]
GO:0050995 [negative regulation of lipid catabolic process]
GO:0051023 [regulation of immunoglobulin secretion]
GO:0051044 [positive regulation of membrane protein ectodomain proteolysis]
GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051222 [positive regulation of protein transport]
GO:0051384 [response to glucocorticoid]
GO:0051533 [positive regulation of NFAT protein import into nucleus]
GO:0051798 [positive regulation of hair follicle development]
GO:0051897 [positive regulation of protein kinase B signaling]
GO:0055037 [recycling endosome]
GO:0060557 [positive regulation of vitamin D biosynthetic process]
GO:0060559 [positive regulation of calcidiol 1-monooxygenase activity]
GO:0060664 [epithelial cell proliferation involved in salivary gland morphogenesis]
GO:0060693 [regulation of branching involved in salivary gland morphogenesis]
GO:0061048 [negative regulation of branching involved in lung morphogenesis]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071230 [cellular response to amino acid stimulus]
GO:0071316 [cellular response to nicotine]
GO:0071407 [cellular response to organic cyclic compound]
GO:0071550 [death-inducing signaling complex assembly]
GO:0071677 [positive regulation of mononuclear cell migration]
GO:0071803 [positive regulation of podosome assembly]
GO:0090002 [establishment of protein localization to plasma membrane]
GO:0097190 [apoptotic signaling pathway]
GO:0097191 [extrinsic apoptotic signaling pathway]
GO:0097527 [necroptotic signaling pathway]
GO:1901224 [positive regulation of NIK/NF-kappaB signaling]
GO:1903140 [regulation of establishment of endothelial barrier]
GO:1903347 [negative regulation of bicellular tight junction assembly]
GO:2000010 [positive regulation of protein localization to cell surface]
GO:2000304 [positive regulation of ceramide biosynthetic process]
GO:2000343 [positive regulation of chemokine (C-X-C motif) ligand 2 production]
GO:2000377 [regulation of reactive oxygen species metabolic process]
GO:2001240 [negative regulation of extrinsic apoptotic signaling pathway in absence of ligand]