Expression of NKX1-1 in cancer - Summary

CANCER ATLAS

Gene description

NK1 homeobox 1

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA029367

GENE INFORMATION
Gene name	NKX1-1 (HGNC Symbol)
Synonyms	HSPX153, SAX2
Description	NK1 homeobox 1 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	p16.3
Chromosome location (bp)	1402932 - 1406331
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000235608 (version 83.38)
Entrez gene	54729
UniProt	Q15270 (UniProt - Evidence at transcript level)
neXtProt	NX_Q15270
Antibodypedia	NKX1-1 antibodies

PROTEIN BROWSER

NKX1-1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NKX1-1-001 ENSP00000407978 ENST00000422806	Q15270 [Direct mapping] NK1 transcription factor-related protein 1 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006629 [lipid metabolic process] GO:0008150 [biological_process] GO:0010906 [regulation of glucose metabolic process] GO:0043467 [regulation of generation of precursor metabolites and energy] GO:0043565 [sequence-specific DNA binding] GO:0050877 [neurological system process] Show all	411 aa 40.7 kDa	No	0