Tissue expression of MFRP - Summary - The Human Protein Atlas

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MFRP

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	MFRP
Gene description	Membrane frizzled-related protein
Protein class	Disease related genes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Not detected
FANTOM5:	Tissue enriched (retina)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA042946
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Not detected
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (retina)

GENE INFORMATION
Gene name	MFRP (HGNC Symbol)
Synonyms	C1QTNF5, FLJ30570, NNO2, rd6
Description	Membrane frizzled-related protein (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the frizzled-related protein family. The encoded protein plays an important role in eye development and mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic transcript which also encodes C1q and tumor necrosis factor related protein 5 (C1QTNF5). [provided by RefSeq, Jun 2013]
Chromosome	11
Cytoband	q23.3
Chromosome location (bp)	119338942 - 119346673
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000235718 (version 83.38)
Entrez gene	83552
UniProt	Q9BY79 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BY79
Antibodypedia	MFRP antibodies

PROTEIN BROWSER

MFRP-001	MFRP-002	MFRP-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MFRP-001 ENSP00000481824 ENST00000619721	Q9BY79 [Direct mapping] Membrane frizzled-related protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0009790 [embryo development] GO:0016021 [integral component of membrane] GO:0016324 [apical plasma membrane] Show all	579 aa 62.2 kDa	No	1
MFRP-002 ENSP00000353291 ENST00000360167	Q9BY79 [Direct mapping] Membrane frizzled-related protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0009790 [embryo development] GO:0016021 [integral component of membrane] GO:0016324 [apical plasma membrane] Show all	461 aa 48.9 kDa	No	1
MFRP-007 ENSP00000391664 ENST00000449574	Q9BY79 [Direct mapping] Membrane frizzled-related protein Show all	Predicted intracellular proteins Disease related genes Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0009790 [embryo development] GO:0016021 [integral component of membrane] GO:0016324 [apical plasma membrane] Show all	188 aa 20.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.