Tissue expression of C2orf74 - Summary - The Human Protein Atlas

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C2orf74

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	C2orf74
Gene description	Chromosome 2 open reading frame 74
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at transcript level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA026826
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	C2orf74 (HGNC Symbol)
Synonyms	LOC339804
Description	Chromosome 2 open reading frame 74 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p15
Chromosome location (bp)	61145068 - 61164829
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000237651 (version 83.38)
Entrez gene	339804
UniProt	A8MZ97 (UniProt - Predicted)
neXtProt	NX_A8MZ97
Antibodypedia	C2orf74 antibodies

PROTEIN BROWSER

C2orf74-001	C2orf74-005	C2orf74-006	C2orf74-007	C2orf74-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C2orf74-001 ENSP00000484061 ENST00000488469	A0A087X1C3 [Direct mapping] Uncharacterized protein C2orf74 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	187 aa 21.2 kDa	No	1
C2orf74-005 ENSP00000398725 ENST00000426997	C9JBF1 [Direct mapping] Uncharacterized protein C2orf74 Show all	Predicted intracellular proteins Show all		115 aa 13.2 kDa	No	0
C2orf74-006 ENSP00000482798 ENST00000464909	C9JBF1 [Direct mapping] Uncharacterized protein C2orf74 Show all	Predicted intracellular proteins Show all		115 aa 13.2 kDa	No	0
C2orf74-007 ENSP00000481253 ENST00000489686	A0A087WXS6 [Direct mapping] Uncharacterized protein C2orf74 Show all	Predicted intracellular proteins Show all		28 aa 3.2 kDa	No	0
C2orf74-201 ENSP00000402915 ENST00000432605	A8MZ97 [Direct mapping] Uncharacterized protein C2orf74 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	194 aa 21.9 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.