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ACAD11

GENERAL INFORMATION

Gene name

 ACAD11

Gene description

 Acyl-CoA dehydrogenase family, member 11

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Not detected
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Granular cytoplasmic expression in selected tissues, most abundant in brain, kidney and liver.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA048317
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ACAD11 (HGNC Symbol)

Synonyms

 FLJ12592

Description

 Acyl-CoA dehydrogenase family, member 11 (HGNC Symbol)

Entrez gene summary

 This gene encodes an acyl-CoA dehydrogenase enzyme with a preference for carbon chain lengths between 20 and 26. Naturally occurring read-through transcription occurs between the upstream gene NPHP3 (nephronophthisis 3 (adolescent)) and this gene. [provided by RefSeq, Aug 2015]

Chromosome

 3

Cytoband

 q22.1

Chromosome location (bp)

 132558138 - 132660723

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000240303 (version 83.38)

Entrez gene

 84129

UniProt

 Q709F0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q709F0

Antibodypedia

 ACAD11 antibodies

PROTEIN BROWSER
ACAD11-001
ACAD11-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ACAD11-001
ENSP00000264990
ENST00000264990
Q709F0 [Direct mapping]
Acyl-CoA dehydrogenase family member 11
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000062 [fatty-acyl-CoA binding]
GO:0003995 [acyl-CoA dehydrogenase activity]
GO:0004466 [long-chain-acyl-CoA dehydrogenase activity]
GO:0005634 [nucleus]
GO:0005743 [mitochondrial inner membrane]
GO:0005777 [peroxisome]
GO:0006635 [fatty acid beta-oxidation]
GO:0008152 [metabolic process]
GO:0009055 [electron carrier activity]
GO:0016627 [oxidoreductase activity, acting on the CH-CH group of donors]
GO:0017099 [very-long-chain-acyl-CoA dehydrogenase activity]
GO:0031966 [mitochondrial membrane]
GO:0033539 [fatty acid beta-oxidation using acyl-CoA dehydrogenase]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0050660 [flavin adenine dinucleotide binding]
GO:0052890 [oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor]
GO:0055088 [lipid homeostasis]
GO:0055114 [oxidation-reduction process]
GO:0070991 [medium-chain-acyl-CoA dehydrogenase activity]
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 780 aa
87.3 kDa 		No 0
ACAD11-005
ENSP00000420907
ENST00000481970
D6RDI8 [Direct mapping]
Acyl-CoA dehydrogenase family member 11
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016627 [oxidoreductase activity, acting on the CH-CH group of donors]
GO:0050660 [flavin adenine dinucleotide binding]
GO:0055114 [oxidation-reduction process]
Show all
 476 aa
53.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.