Expression of PPIL3 in cancer - Summary

CANCER ATLAS

Gene description

Peptidylprolyl isomerase (cyclophilin)-like 3

Protein class

Enzymes, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA040765

GENE INFORMATION
Gene name	PPIL3 (HGNC Symbol)
Synonyms	CyPJ
Description	Peptidylprolyl isomerase (cyclophilin)-like 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2008]
Chromosome	2
Cytoband	q33.1
Chromosome location (bp)	200870907 - 200889303
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000240344 (version 83.38)
Entrez gene	53938
UniProt	Q9H2H8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H2H8
Antibodypedia	PPIL3 antibodies

PROTEIN BROWSER

PPIL3-001	PPIL3-002	PPIL3-006	PPIL3-007	PPIL3-008	PPIL3-011	PPIL3-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PPIL3-001 ENSP00000286175 ENST00000286175	Q9H2H8 [Direct mapping] Peptidyl-prolyl cis-trans isomerase-like 3 Show all	Enzymes ENZYME proteins Isomerase Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000398 [mRNA splicing, via spliceosome] GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0005515 [protein binding] GO:0006457 [protein folding] GO:0071013 [catalytic step 2 spliceosome] Show all	165 aa 18.6 kDa	No	0
PPIL3-002 ENSP00000376107 ENST00000392283	Q9H2H8 [Direct mapping] Peptidyl-prolyl cis-trans isomerase-like 3 A0A024R3V4 [Target identity:100%; Query identity:100%] Peptidyl-prolyl cis-trans isomerase Show all	Enzymes ENZYME proteins Isomerase Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000398 [mRNA splicing, via spliceosome] GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0005515 [protein binding] GO:0006457 [protein folding] GO:0071013 [catalytic step 2 spliceosome] Show all	161 aa 18.2 kDa	No	0
PPIL3-006 ENSP00000386893 ENST00000409264	H7BZ14 [Direct mapping] Peptidyl-prolyl cis-trans isomerase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0006457 [protein folding] Show all	180 aa 20.3 kDa	No	0
PPIL3-007 ENSP00000386235 ENST00000409361	B8ZZ77 [Direct mapping] Peptidyl-prolyl cis-trans isomerase-like 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0006457 [protein folding] Show all	157 aa 17.7 kDa	No	0
PPIL3-008 ENSP00000387012 ENST00000409449	Q9H2H8 [Direct mapping] Peptidyl-prolyl cis-trans isomerase-like 3 Show all	Enzymes ENZYME proteins Isomerase Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000398 [mRNA splicing, via spliceosome] GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0005515 [protein binding] GO:0006457 [protein folding] GO:0071013 [catalytic step 2 spliceosome] Show all	165 aa 18.6 kDa	No	0
PPIL3-011 ENSP00000391082 ENST00000443398	C9J4N2 [Direct mapping] Peptidyl-prolyl cis-trans isomerase-like 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0016021 [integral component of membrane] Show all	73 aa 8.3 kDa	No	1
PPIL3-012 ENSP00000401196 ENST00000457063	C9K058 [Direct mapping] Peptidyl-prolyl cis-trans isomerase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0006457 [protein folding] Show all	80 aa 9 kDa	No	0