Cell atlas - GTF2A1L - The Human Protein Atlas

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GTF2A1L

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	GTF2A1L
Gene description	General transcription factor IIA, 1-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	GTF2A1L (HGNC Symbol)
Synonyms	ALF
Description	General transcription factor IIA, 1-like (HGNC Symbol)
Entrez gene summary	The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of transcription factor IIA (TFIIA) on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Mar 2014]
Chromosome	2
Cytoband	p16.3
Chromosome location (bp)	48617798 - 48733148
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000242441 (version 83.38)
Entrez gene	11036
UniProt	Q9UNN4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UNN4
Antibodypedia	GTF2A1L antibodies

PROTEIN BROWSER

GTF2A1L-001	GTF2A1L-004	GTF2A1L-006	GTF2A1L-007	GTF2A1L-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GTF2A1L-001 ENSP00000384597 ENST00000403751	Q9UNN4 [Direct mapping] TFIIA-alpha and beta-like factor Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005672 [transcription factor TFIIA complex] GO:0005737 [cytoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0050890 [cognition] Show all	478 aa 52.4 kDa	No	0
GTF2A1L-004 ENSP00000412645 ENST00000448460	C9J2C1 [Direct mapping] TFIIA-alpha and beta-like factor Show all	Predicted intracellular proteins Show all	GO:0005672 [transcription factor TFIIA complex] GO:0006367 [transcription initiation from RNA polymerase II promoter] Show all	164 aa 17.9 kDa	No	0
GTF2A1L-006 ENSP00000396702 ENST00000437125	C9JJY0 [Direct mapping] TFIIA-alpha and beta-like factor Show all	Predicted intracellular proteins Show all	GO:0005672 [transcription factor TFIIA complex] GO:0006367 [transcription initiation from RNA polymerase II promoter] Show all	335 aa 36.8 kDa	No	0
GTF2A1L-007 ENSP00000421474 ENST00000508440	H0Y8M0 [Direct mapping] TFIIA-alpha and beta-like factor Show all	Predicted intracellular proteins Show all	GO:0005672 [transcription factor TFIIA complex] GO:0006367 [transcription initiation from RNA polymerase II promoter] Show all	102 aa 11.1 kDa	No	0
GTF2A1L-201 ENSP00000387896 ENST00000430487	Q9UNN4 [Direct mapping] TFIIA-alpha and beta-like factor Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005672 [transcription factor TFIIA complex] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006367 [transcription initiation from RNA polymerase II promoter] GO:0050890 [cognition] Show all	444 aa 48.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.