Expression of TTC4 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Tetratricopeptide repeat domain 4

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041608	HPA042459

GENE INFORMATION
Gene name	TTC4 (HGNC Symbol)
Synonyms	FLJ41930, MGC5097
Description	Tetratricopeptide repeat domain 4 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity. The encoded protein interacts with heat shock proteins 70 and 90. Alternative splicing results in multiple transcript variants. Naturally-occuring readthrough transcription occurs from upstream gene MROH (maestro heat-like repeat family member 7) to this gene. [provided by RefSeq, Apr 2014]
Chromosome	1
Cytoband	p32.3
Chromosome location (bp)	54715822 - 54742657
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000243725 (version 83.38)
Entrez gene	7268
UniProt	O95801 (UniProt - Evidence at protein level)
neXtProt	NX_O95801
Antibodypedia	TTC4 antibodies

PROTEIN BROWSER

TTC4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TTC4-001 ENSP00000360329 ENST00000371281	O95801 [Direct mapping] Tetratricopeptide repeat protein 4 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	387 aa 44.7 kDa	No	0